This work is licensed under a Creative Commons Attribution 4.0 International License.
Nicomicin-1
General Information
DRACP ID DRACP03753
Peptide Name Nicomicin-1
Sequence GFWSSVWDGAKNVGTAIIKNAKVCVYAVCVSHK
Sequence Length 33
UniProt ID A0A3G2WH77
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C161H249N43O43S2
Absent amino acids ELMPQR
Common amino acids V
Mass 411011
Pl 9.43
Basic residues 5
Acidic residues 1
Hydrophobic residues 15
Net charge 4
Boman Index -743
Hydrophobicity 37.88
Aliphatic Index 88.48
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 12615
Absorbance 280nm 394.22
Polar residues 12
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30360541
Title Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12236
This work is licensed under a Creative Commons Attribution 4.0 International License.