Nicomicin-1 (1-17)

General Information


DRACP ID  DRACP03754

Peptide Name   Nicomicin-1 (1-17)

Sequence  GFWSSVWDGAKNVGTAI

Sequence Length  17

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C83H119N21O24

Absent amino acids  CEHLMPQRY

Common amino acids  G

Mass  208056

Pl  6.34

Basic residues  1

Acidic residues  1

Hydrophobic residues  8

Net charge  0

Boman Index  -320

Hydrophobicity  18.24

Aliphatic Index  68.82

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  11000

Absorbance 280nm  687.5

Polar residues  7

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 30360541

Title  Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain

Doi Not available

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12237

DRACP is developed by Dr.Zheng's team.