This work is licensed under a Creative Commons Attribution 4.0 International License.
Nicomicin-1 (18-33)
General Information
DRACP ID DRACP03755
Peptide Name Nicomicin-1 (18-33)
Sequence IKNAKVCVYAVCVSHK
Sequence Length 16
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C78H132N22O20S2
Absent amino acids DEFGLMPQRTW
Common amino acids V
Mass 202991
Pl 9.46
Basic residues 4
Acidic residues 0
Hydrophobic residues 7
Net charge 4
Boman Index -423
Hydrophobicity 58.75
Aliphatic Index 109.38
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1615
Absorbance 280nm 107.67
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30360541
Title Novel Antimicrobial Peptides from the Arctic Polychaeta Nicomache minor Provide New Molecular Insight into Biological Role of the BRICHOS Domain
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12238
This work is licensed under a Creative Commons Attribution 4.0 International License.