This work is licensed under a Creative Commons Attribution 4.0 International License.
Anti-lipopolysaccharide factor (32-51)[Y2A,P6p,L11l], CIGB-552
General Information
DRACP ID DRACP03757
Peptide Name Anti-lipopolysaccharide factor (32-51)[Y2A,P6p,L11l], CIGB-552
Sequence HARIKpTFRRlKWKYKGKFW
Sequence Length 20
UniProt ID P07086
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C118H174N36O19
Absent amino acids CDELMNPQSV
Common amino acids K
Mass 273997
Pl 12.3
Basic residues 9
Acidic residues 0
Hydrophobic residues 6
Net charge 9
Boman Index -6159
Hydrophobicity -142.5
Aliphatic Index 24.5
Half Life
/
Extinction Coefficient cystines 12490
Absorbance 280nm 657.37
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29601540
Title Cell Penetrating Capacity and Internalization Mechanisms Used by the Synthetic peptide Peptide CIGB-552 and Its Relationship with Tumor Cell Line Sensitivity
Doi Not available
Year 2018
Literature 2
Pubmed ID 23401744
Title The Antitumor Peptide CIGB-552 Increases COMMD1 and Inhibits Growth of Human Lung Cancer Cells
Doi Not available
Year 2013
Literature 3
Pubmed ID 30481557
Title Evidence for antimicrobial and anticancer activity of pituitary adenylate cyclase-activating polypeptide (PACAP) from North African catfish (Clarias gariepinus): Its potential use as novel therapeutic agent in fish and humans
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12310
This work is licensed under a Creative Commons Attribution 4.0 International License.