This work is licensed under a Creative Commons Attribution 4.0 International License.
Esculentin-1GN
General Information
DRACP ID DRACP03769
Peptide Name Esculentin-1GN
Sequence GLFSKKGGKGGKSWIKGVFKGIKGIGKEVGGDVIRTGIEIAACKIKGEC
Sequence Length 49
UniProt ID A0A3G6VAR4
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C225H379N63O61S2
Absent amino acids HMNPQY
Common amino acids G
Mass 586337
Pl 10.63
Basic residues 11
Acidic residues 4
Hydrophobic residues 16
Net charge 7
Boman Index -3077
Hydrophobicity -7.76
Aliphatic Index 85.51
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5625
Absorbance 280nm 117.19
Polar residues 18
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30427189
Title Functional Characterization of a Novel Lipopolysaccharide-Binding Antimicrobial and Anti-Inflammatory Peptide in Vitro and in Vivo
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12416
This work is licensed under a Creative Commons Attribution 4.0 International License.