This work is licensed under a Creative Commons Attribution 4.0 International License.
Bactenecin-5 (1-17), Bac5(1-17)
General Information
DRACP ID DRACP03778
Peptide Name Bactenecin-5 (1-17), Bac5(1-17)
Sequence RFRPPIRRPPIRPPFYP
Sequence Length 17
UniProt ID P19660
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C104H160N32O19
Absent amino acids ACDEGHKLMNQSTVW
Common amino acids P
Mass 244814
Pl 12.68
Basic residues 5
Acidic residues 0
Hydrophobic residues 4
Net charge 5
Boman Index -5894
Hydrophobicity -120
Aliphatic Index 45.88
Half Life
Mammalian: 1.1 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 1490
Absorbance 280nm 93.13
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31692278
Title Proline-Rich Peptides With Improved Antimicrobial Activity Against E Coli, K Pneumoniae, and A Baumannii
Doi Not available
Year 2019
Literature 2
Pubmed ID 30615305
Title Search for Shorter Portions of the Proline-Rich Antimicrobial Peptide Fragment Bac5(1-25) That Retain Antimicrobial Activity by Blocking Protein Synthesis
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12577
This work is licensed under a Creative Commons Attribution 4.0 International License.