This work is licensed under a Creative Commons Attribution 4.0 International License.
pEM-2 [W5K,K8W9L10Del]
General Information
DRACP ID DRACP03779
Peptide Name pEM-2 [W5K,K8W9L10Del]
Sequence KKWRKWLAKK
Sequence Length 10
UniProt ID P24605
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Acetylation
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C67H110N20O11
Absent amino acids CDEFGHIMNPQSTVY
Common amino acids K
Mass 153245
Pl 12.05
Basic residues 6
Acidic residues 0
Hydrophobic residues 4
Net charge 6
Boman Index -3128
Hydrophobicity -202
Aliphatic Index 49
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 11000
Absorbance 280nm 1222.22
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 34733262
Title Boosting Synergistic Effects of Short Antimicrobial Peptides With Conventional Antibiotics Against Resistant Bacteria
Doi Not available
Year 2021
Literature 2
Pubmed ID 23716061
Title Boosting salt resistance of short antimicrobial peptides
Doi Not available
Year 2013
Literature 3
Pubmed ID 25970292
Title Novel antimicrobial peptides with high anticancer activity and selectivity
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12587
This work is licensed under a Creative Commons Attribution 4.0 International License.