W4

General Information


DRACP ID  DRACP03787

Peptide Name   W4

Sequence  RWRWWWRWR

Sequence Length  9

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C79H100N26O10

Absent amino acids  ACDEFGHIKLMNPQSTVY

Common amino acids  W

Mass  171669

Pl  12.98

Basic residues  4

Acidic residues  0

Hydrophobic residues  5

Net charge  4

Boman Index  -4803

Hydrophobicity  -250

Aliphatic Index  0

Half Life 
  Mammalian: 20 hour
  Yeast: 30 min
  E.coli: >10 hour

Extinction Coefficient cystines  27500

Absorbance 280nm  3437.5

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 36649429

Title  Synthetic peptide peptides that form nanostructured micelles have potent antibiotic and antibiofilm activity against polymicrobial infections

Doi Not available

Year  2023

Literature 2

Pubmed ID 29648811

Title  Combating Drug-Resistant Fungi with Novel Imperfectly Amphipathic Palindromic Peptides

Doi Not available

Year  2018

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12599

DRACP is developed by Dr.Zheng's team.