This work is licensed under a Creative Commons Attribution 4.0 International License.
Japonicin-2LF
General Information
DRACP ID DRACP03797
Peptide Name Japonicin-2LF
Sequence FIVPSIFLLKKAFCIALKKC
Sequence Length 20
UniProt ID A0A482F245
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C112H184N24O22S2
Absent amino acids DEGHMNQRTWY
Common amino acids K
Mass 262206
Pl 10.35
Basic residues 4
Acidic residues 0
Hydrophobic residues 12
Net charge 4
Boman Index 2308
Hydrophobicity 140.5
Aliphatic Index 141.5
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 125
Absorbance 280nm 6.58
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30802593
Title A novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12644
This work is licensed under a Creative Commons Attribution 4.0 International License.