This work is licensed under a Creative Commons Attribution 4.0 International License.
KK-Temporin-B [G6A]
General Information
DRACP ID DRACP03801
Peptide Name KK-Temporin-B [G6A]
Sequence KKLLPIVANLLKSLL
Sequence Length 15
UniProt ID P79874
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C80H147N19O18
Absent amino acids CDEFGHMQRTWY
Common amino acids L
Mass 191308
Pl 11.1
Basic residues 3
Acidic residues 0
Hydrophobic residues 9
Net charge 3
Boman Index 1360
Hydrophobicity 104.67
Aliphatic Index 208
Half Life
Mammalian: 20 hour
Yeast: 30 min
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28443279
Title Analogs of the Frog-skin Antimicrobial Peptide Temporin 1Tb Exhibit a Wider Spectrum of Activity and a Stronger Antibiofilm Potential as Compared to the Parental Peptide
Doi Not available
Year 2017
Literature 2
Pubmed ID 30718667
Title Minor sequence modifications in temporin B cause drastic changes in antibacterial potency and selectivity by fundamentally altering membrane activity
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12687
This work is licensed under a Creative Commons Attribution 4.0 International License.