SMAP-29 (1-18)
General Information
DRACP ID DRACP03805
Peptide Name SMAP-29 (1-18)
Sequence RGLRRLGRKIAHGVKKYG
Sequence Length 18
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C91H161N35O20
Absent amino acids CDEFMNPQSTW
Common amino acids GR
Mass 236891
Pl 12.53
Basic residues 8
Acidic residues 0
Hydrophobic residues 5
Net charge 8
Boman Index -5676
Hydrophobicity -98.33
Aliphatic Index 86.67
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 1490
Absorbance 280nm 87.65
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26795535
Title The Stereochemical Effect of SMAP-29 and SMAP-18 on Bacterial Selectivity, Membrane Interaction and Anti-Inflammatory Activity
Doi Not available
Year 2016
Literature 2
Pubmed ID 24221355
Title Bacterial killing mechanism of sheep myeloid antimicrobial peptide-18 (SMAP-18) and its Trp-substituted analog with improved cell selectivity and reduced mammalian cell toxicity
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12780