SMAP-29 (1-18)

General Information


DRACP ID  DRACP03805

Peptide Name   SMAP-29 (1-18)

Sequence  RGLRRLGRKIAHGVKKYG

Sequence Length  18

UniProt ID  P49929  P49928 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C91H161N35O20

Absent amino acids  CDEFMNPQSTW

Common amino acids  GR

Mass  236891

Pl  12.53

Basic residues  8

Acidic residues  0

Hydrophobic residues  5

Net charge  8

Boman Index  -5676

Hydrophobicity  -98.33

Aliphatic Index  86.67

Half Life 
  Mammalian:
  Yeast:
  E.coli:

Extinction Coefficient cystines  1490

Absorbance 280nm  87.65

Polar residues  5

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 26795535

Title  The Stereochemical Effect of SMAP-29 and SMAP-18 on Bacterial Selectivity, Membrane Interaction and Anti-Inflammatory Activity

Doi Not available

Year  2016

Literature 2

Pubmed ID 24221355

Title  Bacterial killing mechanism of sheep myeloid antimicrobial peptide-18 (SMAP-18) and its Trp-substituted analog with improved cell selectivity and reduced mammalian cell toxicity

Doi Not available

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  12780

DRACP is developed by Dr.Zheng's team.