This work is licensed under a Creative Commons Attribution 4.0 International License.
SMAP-29 (1-18)[L3,6W][I10W][V14W]
General Information
DRACP ID DRACP03806
Peptide Name SMAP-29 (1-18)[L3,6W][I10W][V14W]
Sequence RGWRRWGRKWAHGWKKYG
Sequence Length 18
UniProt ID P49928
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C112H159N39O20
Absent amino acids CDEFILMNPQSTV
Common amino acids GRW
Mass 267514
Pl 12.53
Basic residues 8
Acidic residues 0
Hydrophobic residues 5
Net charge 8
Boman Index -6624
Hydrophobicity -208.89
Aliphatic Index 5.56
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 23490
Absorbance 280nm 1381.76
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24221355
Title Bacterial killing mechanism of sheep myeloid antimicrobial peptide-18 (SMAP-18) and its Trp-substituted analog with improved cell selectivity and reduced mammalian cell toxicity
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12781
This work is licensed under a Creative Commons Attribution 4.0 International License.