Mitoparan [L14S], Mastoparan [A5,8K;A10Aib;L14S]
General Information
DRACP ID DRACP03807
Peptide Name Mitoparan [L14S], Mastoparan [A5,8K;A10Aib;L14S]
Sequence INLKKLAKLXKKIS
Sequence Length 14
UniProt ID P01514
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C70H131N19O15
Absent amino acids CDEFGHMPQRTVWY
Common amino acids K
Mass 182100
Pl 11.4
Basic residues 5
Acidic residues 0
Hydrophobic residues 6
Net charge 5
Boman Index -1138
Hydrophobicity -11.43
Aliphatic Index 146.43
Half Life
/
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29337270
Title The cationic tetradecapeptide mastoparan as a privileged structure for drug discovery: Enhanced antimicrobial properties of mitoparan analogues modified at position-14
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12796