This work is licensed under a Creative Commons Attribution 4.0 International License.
MK58911
General Information
DRACP ID DRACP03811
Peptide Name MK58911
Sequence INWLKIAKKVKGML
Sequence Length 14
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C78H136N20O16S
Absent amino acids CDEFHPQRSTY
Common amino acids K
Mass 187420
Pl 11.28
Basic residues 4
Acidic residues 0
Hydrophobic residues 7
Net charge 4
Boman Index 231
Hydrophobicity 29.29
Aliphatic Index 139.29
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 423.08
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31512522
Title Study of mastoparan analog peptides against Candida albicans and safety in zebrafish embryos (Danio rerio)
Doi Not available
Year 2019
Literature 2
Pubmed ID 31867293
Title Antifungal Activity, Toxicity, and Membranolytic Action of a Mastoparan Analog Peptide
Doi Not available
Year 2019
Literature 3
Pubmed ID 25944744
Title Structure-activity relationship of mastoparan analogs: Effects of the number and positioning of Lys residues on secondary structure, interaction with membrane-mimetic systems and biological activity
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 12838
This work is licensed under a Creative Commons Attribution 4.0 International License.