Cecropin-B [E27Q]

General Information


DRACP ID  DRACP03820

Peptide Name   Cecropin-B [E27Q]

Sequence  RWKIFKKIEKMGRNIRDGIVKAGPAIQVLGSAKAI

Sequence Length  35

UniProt ID  P04142 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C177H303N53O43S

Absent amino acids  CHTY

Common amino acids  IK

Mass  450040

Pl  11.82

Basic residues  9

Acidic residues  2

Hydrophobic residues  15

Net charge  7

Boman Index  -4799

Hydrophobicity  -13.43

Aliphatic Index  106

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  5500

Absorbance 280nm  161.76

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31045339

Title  Enhanced Silkworm Cecropin B Antimicrobial Activity against Pseudomonas aeruginosa from Single Amino Acid Variation

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  13146

DRACP is developed by Dr.Zheng's team.