Lugdunin
General Information
DRACP ID DRACP03825
Peptide Name Lugdunin
Sequence CvWlVvV
Sequence Length 7
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral Mix
Physicochemical Information
Formula C24H29N5O2S
Absent amino acids ADEFGHIKLMNPQRSTY
Common amino acids V
Mass 55879
Pl 5.92
Basic residues 0
Acidic residues 0
Hydrophobic residues 3
Net charge 0
Boman Index 1169
Hydrophobicity 142.86
Aliphatic Index 82.86
Half Life
/
Extinction Coefficient cystines 5500
Absorbance 280nm 916.67
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 35887376
Title Antibacterial and Antibiofilm Activities of Novel Cyclic Peptides against Methicillin-Resistant Staphylococcus aureus
Doi Not available
Year 2022
Literature 2
Pubmed ID 31059155
Title Synthetic peptide Lugdunin Analogues Reveal Essential Structural Motifs for Antimicrobial Action and Proton Translocation Capability
Doi Not available
Year 2019
Literature 3
Pubmed ID 27466123
Title Human commensals producing a novel antibiotic impair pathogen colonization
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13304