Lugdunin

General Information


DRACP ID  DRACP03825

Peptide Name   Lugdunin

Sequence  CvWlVvV

Sequence Length  7

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Native peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  Mix



Physicochemical Information


Formula  C24H29N5O2S

Absent amino acids  ADEFGHIKLMNPQRSTY

Common amino acids  V

Mass  55879

Pl  5.92

Basic residues  0

Acidic residues  0

Hydrophobic residues  3

Net charge  0

Boman Index  1169

Hydrophobicity  142.86

Aliphatic Index  82.86

Half Life 
  /

Extinction Coefficient cystines  5500

Absorbance 280nm  916.67

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 35887376

Title  Antibacterial and Antibiofilm Activities of Novel Cyclic Peptides against Methicillin-Resistant Staphylococcus aureus

Doi Not available

Year  2022

Literature 2

Pubmed ID 31059155

Title  Synthetic peptide Lugdunin Analogues Reveal Essential Structural Motifs for Antimicrobial Action and Proton Translocation Capability

Doi Not available

Year  2019

Literature 3

Pubmed ID 27466123

Title  Human commensals producing a novel antibiotic impair pathogen colonization

Doi Not available

Year  2016

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  13304

DRACP is developed by Dr.Zheng's team.