This work is licensed under a Creative Commons Attribution 4.0 International License.
FhHDM-1p2
General Information
DRACP ID DRACP03828
Peptide Name FhHDM-1p2
Sequence AMAYLAKDNLGEKITEVITILLNRLTDRLEKYAG
Sequence Length 34
UniProt ID F6KNY7
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antiparasitic
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C171H287N45O52S
Absent amino acids CFHPQSW
Common amino acids L
Mass 442632
Pl 6.66
Basic residues 5
Acidic residues 5
Hydrophobic residues 14
Net charge 0
Boman Index -4584
Hydrophobicity -3.24
Aliphatic Index 123.53
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 2980
Absorbance 280nm 90.3
Polar residues 9
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23875042
Title Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13415
This work is licensed under a Creative Commons Attribution 4.0 International License.