This work is licensed under a Creative Commons Attribution 4.0 International License.
SmHDM-1p146
General Information
DRACP ID DRACP03830
Peptide Name SmHDM-1p146
Sequence IDTYSRKDDLDKKLLEVAKIIGRRLEKRHEYLAMK
Sequence Length 35
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C188H319N55O54S
Absent amino acids CFNPQW
Common amino acids K
Mass 485265
Pl 10.11
Basic residues 11
Acidic residues 7
Hydrophobic residues 11
Net charge 4
Boman Index -10889
Hydrophobicity -89.71
Aliphatic Index 103.14
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 2980
Absorbance 280nm 87.65
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23875042
Title Cathelicidin-like helminth defence molecules (HDMs): absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation
Doi Not available
Year 2013
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13417
This work is licensed under a Creative Commons Attribution 4.0 International License.