This work is licensed under a Creative Commons Attribution 4.0 International License.
Arenicin-1 [V4R; Y5,7R; A6Y; R16,18Y; Y17A; R19V]
General Information
DRACP ID DRACP03837
Peptide Name Arenicin-1 [V4R; Y5,7R; A6Y; R16,18Y; Y17A; R19V]
Sequence RWCRRYRVRVRGVLVYAYVCW
Sequence Length 21
UniProt ID Q5SC60
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C127H195N41O25S2
Absent amino acids DEFHIKMNPQST
Common amino acids R
Mass 311723
Pl 11.15
Basic residues 6
Acidic residues 0
Hydrophobic residues 9
Net charge 6
Boman Index -5485
Hydrophobicity -7.14
Aliphatic Index 92.38
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 15595
Absorbance 280nm 779.75
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31234579
Title Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13505
This work is licensed under a Creative Commons Attribution 4.0 International License.