This work is licensed under a Creative Commons Attribution 4.0 International License.
R-Arenicin-1 [L15R; R17,19Y; Y18A; R20V]
General Information
DRACP ID DRACP03838
Peptide Name R-Arenicin-1 [L15R; R17,19Y; Y18A; R20V]
Sequence RRWCVYAYVRVRGVRVYAYVCW
Sequence Length 22
UniProt ID Q5SC60
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C132H195N39O27S2
Absent amino acids DEFHIKLMNPQST
Common amino acids V
Mass 319911
Pl 10.12
Basic residues 5
Acidic residues 0
Hydrophobic residues 10
Net charge 5
Boman Index -3914
Hydrophobicity 17.73
Aliphatic Index 88.18
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 17085
Absorbance 280nm 813.57
Polar residues 7
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31234579
Title Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13506
This work is licensed under a Creative Commons Attribution 4.0 International License.