Arenicin (2-21) [V3R; Y4,6R; A5Y; R8L]

General Information


DRACP ID  DRACP03839

Peptide Name   Arenicin (2-21) [V3R; Y4,6R; A5Y; R8L]

Sequence  WCRRYRVLVRGVLVRYRRCW

Sequence Length  20

UniProt ID  Q5SC60 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C122H195N43O23S2

Absent amino acids  ADEFHIKMNPQST

Common amino acids  R

Mass  303535

Pl  12.11

Basic residues  7

Acidic residues  0

Hydrophobic residues  8

Net charge  7

Boman Index  -7056

Hydrophobicity  -34.5

Aliphatic Index  97

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  14105

Absorbance 280nm  742.37

Polar residues  5

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31234579

Title  Redesigning Arenicin-1, an Antimicrobial Peptide from the Marine Polychaeta Arenicola marina, by Strand Rearrangement or Branching, Substitution of Specific Residues, and Backbone Linearization or Cyclization

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  13507

DRACP is developed by Dr.Zheng's team.