Oncocin [D2R,P12W,P13Hyp,R15Hyp,I16Tle,R19Orn]
General Information
DRACP ID DRACP03844
Peptide Name Oncocin [D2R,P12W,P13Hyp,R15Hyp,I16Tle,R19Orn]
Sequence VRKPPYLPRPRWXRXXYNX
Sequence Length 19
UniProt ID A0A2R7WNA0
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C94H136N30O15
Absent amino acids ACDEFGHIMQST
Common amino acids PRX
Mass 268751
Pl 12.06
Basic residues 5
Acidic residues 0
Hydrophobic residues 3
Net charge 5
Boman Index -6086
Hydrophobicity -143.68
Aliphatic Index 35.79
Half Life
/
Extinction Coefficient cystines 8480
Absorbance 280nm 471.11
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26334348
Title Optimization of oncocin for antibacterial activity using a SPOT synthesis approach: extending the pathogen spectrum to Staphylococcus aureus
Doi Not available
Year 2016
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13593