This work is licensed under a Creative Commons Attribution 4.0 International License.
AcrAP1, AP1-Z1
General Information
DRACP ID DRACP03851
Peptide Name AcrAP1, AP1-Z1
Sequence FLFSLIPHAISGLISAFK
Sequence Length 18
UniProt ID A0A0A1I6E7
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C97H149N21O22
Absent amino acids CDEMNQRTVWY
Common amino acids FILS
Mass 226479
Pl 9.7
Basic residues 2
Acidic residues 0
Hydrophobic residues 11
Net charge 2
Boman Index 2261
Hydrophobicity 141.11
Aliphatic Index 141.11
Half Life
Mammalian: 1.9 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 4
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31909181
Title In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide
Doi Not available
Year 2019
Literature 2
Pubmed ID 25332684
Title Cationicity-enhanced analogues of the antimicrobial peptides, AcrAP1 and AcrAP2, from the venom of the scorpion, Androctonus crassicauda, display potent growth modulation effects on human cancer cell lines
Doi Not available
Year 2014
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13647
This work is licensed under a Creative Commons Attribution 4.0 International License.