This work is licensed under a Creative Commons Attribution 4.0 International License.
Human Defensin-5/HD5 [E21R]
General Information
DRACP ID DRACP03857
Peptide Name Human Defensin-5/HD5 [E21R]
Sequence ATCYCRTGRCATRESLSGVCRISGRLYRLCCR
Sequence Length 32
UniProt ID Q01523
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C145H249N53O43S6
Absent amino acids DFHKMNPQW
Common amino acids R
Mass 416838
Pl 9.19
Basic residues 7
Acidic residues 1
Hydrophobic residues 7
Net charge 6
Boman Index -9160
Hydrophobicity -14.38
Aliphatic Index 64.06
Half Life
Mammalian:
Yeast:
E.coli:
Extinction Coefficient cystines 3355
Absorbance 280nm 108.23
Polar residues 17
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 23269800
Title Enhancement of antiviral activity of human alpha-defensin 5 against herpes simplex virus 2 by arginine mutagenesis at adaptive evolution sites
Doi Not available
Year 2013
Literature 2
Pubmed ID 25782105
Title Design of a potent antibiotic peptide based on the active region of human defensin 5
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13710
This work is licensed under a Creative Commons Attribution 4.0 International License.