This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclic Tachyplesin-2
General Information
DRACP ID DRACP03867
Peptide Name Cyclic Tachyplesin-2
Sequence RWCFRVCYRGICYRKCRG
Sequence Length 18
UniProt ID P14214
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C101H157N35O21S4
Absent amino acids ADEHLMNPQST
Common amino acids R
Mass 262922
Pl 10.07
Basic residues 6
Acidic residues 0
Hydrophobic residues 4
Net charge 6
Boman Index -5916
Hydrophobicity -51.11
Aliphatic Index 37.78
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 8730
Absorbance 280nm 513.53
Polar residues 8
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31455019
Title Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13890
This work is licensed under a Creative Commons Attribution 4.0 International License.