Cyclic Tachyplesin-3

General Information


DRACP ID  DRACP03868

Peptide Name   Cyclic Tachyplesin-3

Sequence  KWCFRVCYRGICYRKCRG

Sequence Length  18

UniProt ID  P14214 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  6PIP 

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C101H157N33O21S4

Absent amino acids  ADEHLMNPQST

Common amino acids  CR

Mass  260121

Pl  9.99

Basic residues  6

Acidic residues  0

Hydrophobic residues  4

Net charge  6

Boman Index  -4979

Hydrophobicity  -47.78

Aliphatic Index  37.78

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  8730

Absorbance 280nm  513.53

Polar residues  8

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31455019

Title  Characterization of Tachyplesin Peptides and Their Cyclized Analogues to Improve Antimicrobial and Anticancer Properties

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  13891

DRACP is developed by Dr.Zheng's team.