PMAP-36 (2-17) [K7,11W]-Fowlicidin, Myeloid antimicrobial peptide 27 (1-15)
General Information
DRACP ID DRACP03879
Peptide Name PMAP-36 (2-17) [K7,11W]-Fowlicidin, Myeloid antimicrobial peptide 27 (1-15)
Sequence RFRRLRWKTRWRLKKIRFGRFLRKIRRFRPK
Sequence Length 31
UniProt ID P49931
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C201H334N74O33
Absent amino acids ACDEHMNQSVY
Common amino acids R
Mass 485057
Pl 13.55
Basic residues 17
Acidic residues 0
Hydrophobic residues 11
Net charge 17
Boman Index -16724
Hydrophobicity -149.68
Aliphatic Index 62.9
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 11000
Absorbance 280nm 366.67
Polar residues 2
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25818457
Title Characterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of ?-helix-based peptide amphiphiles
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13911