PMAP-36 (2-17) [K7,11W]-Fowlicidin, Myeloid antimicrobial peptide 27 (1-15)

General Information


DRACP ID  DRACP03879

Peptide Name   PMAP-36 (2-17) [K7,11W]-Fowlicidin, Myeloid antimicrobial peptide 27 (1-15)

Sequence  RFRRLRWKTRWRLKKIRFGRFLRKIRRFRPK

Sequence Length  31

UniProt ID  P49931 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C201H334N74O33

Absent amino acids  ACDEHMNQSVY

Common amino acids  R

Mass  485057

Pl  13.55

Basic residues  17

Acidic residues  0

Hydrophobic residues  11

Net charge  17

Boman Index  -16724

Hydrophobicity  -149.68

Aliphatic Index  62.9

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  11000

Absorbance 280nm  366.67

Polar residues  2

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 25818457

Title  Characterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of ?-helix-based peptide amphiphiles

Doi Not available

Year  2015

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  13911

DRACP is developed by Dr.Zheng's team.