This work is licensed under a Creative Commons Attribution 4.0 International License.
PMAP-36 (2-17) [K7,11W]-Protegrin-3 (6-16)
General Information
DRACP ID DRACP03880
Peptide Name PMAP-36 (2-17) [K7,11W]-Protegrin-3 (6-16)
Sequence RFRRLRWKTRWRLKKICYCRRRFCVCV
Sequence Length 27
UniProt ID P49931
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C165H271N59O30S4
Absent amino acids ADEGHMNPQS
Common amino acids R
Mass 415350
Pl 12.22
Basic residues 12
Acidic residues 0
Hydrophobic residues 9
Net charge 12
Boman Index -11506
Hydrophobicity -73.7
Aliphatic Index 64.81
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 12740
Absorbance 280nm 490
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25818457
Title Characterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of ?-helix-based peptide amphiphiles
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13912
This work is licensed under a Creative Commons Attribution 4.0 International License.