PMAP-36 (2-17) [K7,11W]-Tritrpticin (7-13)
General Information
DRACP ID DRACP03881
Peptide Name PMAP-36 (2-17) [K7,11W]-Tritrpticin (7-13)
Sequence RFRRLRWKTRWRLKKIWWPFLRR
Sequence Length 23
UniProt ID P51524
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C161H250N54O25
Absent amino acids ACDEGHMNQSVY
Common amino acids R
Mass 373466
Pl 13.35
Basic residues 11
Acidic residues 0
Hydrophobic residues 10
Net charge 11
Boman Index -10362
Hydrophobicity -139.57
Aliphatic Index 67.83
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 22000
Absorbance 280nm 1000
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 25818457
Title Characterization of cell selectivity, physiological stability and endotoxin neutralization capabilities of ?-helix-based peptide amphiphiles
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 13913