L2W
General Information
DRACP ID DRACP03888
Peptide Name L2W
Sequence LRRLRRRLRRLRRRWRRRLRRLRRRLRRL
Sequence Length 29
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C179H340N90O30
Absent amino acids ACDEFGHIKMNPQSTVY
Common amino acids R
Mass 473281
Pl 13.78
Basic residues 20
Acidic residues 0
Hydrophobic residues 9
Net charge 20
Boman Index -25671
Hydrophobicity -208.62
Aliphatic Index 107.59
Half Life
Mammalian: 5.5 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 196.43
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 28230992
Title Novel Design of Heptad Amphiphiles To Enhance Cell Selectivity, Salt Resistance, Antibiofilm Properties and Their Membrane-Disruptive Mechanism
Doi Not available
Year 2017
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14003