L2W

General Information


DRACP ID  DRACP03888

Peptide Name   L2W

Sequence  LRRLRRRLRRLRRRWRRRLRRLRRRLRRL

Sequence Length  29

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C179H340N90O30

Absent amino acids  ACDEFGHIKMNPQSTVY

Common amino acids  R

Mass  473281

Pl  13.78

Basic residues  20

Acidic residues  0

Hydrophobic residues  9

Net charge  20

Boman Index  -25671

Hydrophobicity  -208.62

Aliphatic Index  107.59

Half Life 
  Mammalian: 5.5 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  196.43

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 28230992

Title  Novel Design of Heptad Amphiphiles To Enhance Cell Selectivity, Salt Resistance, Antibiofilm Properties and Their Membrane-Disruptive Mechanism

Doi Not available

Year  2017

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  14003

DRACP is developed by Dr.Zheng's team.