This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin-PS4, Der-PS4
General Information
DRACP ID DRACP03897
Peptide Name Dermaseptin-PS4, Der-PS4
Sequence ALWKTLLKHVGKAAGKAALNAVTDMVNQ
Sequence Length 28
UniProt ID A0A5C0B7V8
PubChem CID Not available
Origin Animalia
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C132H222N38O36S
Absent amino acids CEFIPRSY
Common amino acids A
Mass 343133
Pl 10.8
Basic residues 5
Acidic residues 1
Hydrophobic residues 14
Net charge 4
Boman Index -1032
Hydrophobicity 16.43
Aliphatic Index 108.21
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 203.7
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31426323
Title Evaluating the Bioactivity of a Novel Antimicrobial and Anticancer Peptide, Dermaseptin-PS4(Der-PS4), from the Skin Secretion of Phyllomedusa sauvagii
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14048
This work is licensed under a Creative Commons Attribution 4.0 International License.