Indolicidin [P7K, W9T]

General Information


DRACP ID  DRACP03900

Peptide Name   Indolicidin [P7K, W9T]

Sequence  ILPWKWKWTPWRR

Sequence Length  13

UniProt ID  P33046 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  5ZVF 

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C94H133N25O15

Absent amino acids  ACDEFGHMNQSVY

Common amino acids  W

Mass  206746

Pl  12.53

Basic residues  4

Acidic residues  0

Hydrophobic residues  6

Net charge  4

Boman Index  -2435

Hydrophobicity  -123.08

Aliphatic Index  60

Half Life 
  Mammalian: 100 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  22000

Absorbance 280nm  1833.33

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31485742

Title  Design of therapeutically improved analogue of the antimicrobial peptide, indolicidin, using a glycosylation strategy

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  14078

DRACP is developed by Dr.Zheng's team.