This work is licensed under a Creative Commons Attribution 4.0 International License.
Melittin [L6,13NLYS; I20NLYS]
General Information
DRACP ID DRACP03903
Peptide Name Melittin [L6,13NLYS; I20NLYS]
Sequence GIGAVXKVLTTGXPALISWXKRKRQQ
Sequence Length 26
UniProt ID Q95Z19
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C113H189N35O26
Absent amino acids CDEFHMNY
Common amino acids GKX
Mass 323007
Pl 12.55
Basic residues 5
Acidic residues 0
Hydrophobic residues 9
Net charge 5
Boman Index -2958
Hydrophobicity -19.23
Aliphatic Index 90
Half Life
/
Extinction Coefficient cystines 5500
Absorbance 280nm 220
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 17462584
Title Substitution of the leucine zipper sequence in melittin with peptoid residues affects self-association, cell selectivity, and mode of action
Doi Not available
Year 2007
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14133
This work is licensed under a Creative Commons Attribution 4.0 International License.