Ribonuclease 7 (1-45) [C23,37S; K1,3,12, 28,32,35,38,R]

General Information


DRACP ID  DRACP03905

Peptide Name   Ribonuclease 7 (1-45) [C23,37S; K1,3,12, 28,32,35,38,R]

Sequence  RPRGMTSSQWFRIQHMQPSPQASNSAMRNINRHTRRSRDLNTFLH

Sequence Length  45

UniProt ID  Q9H1E1 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C227H364N84O65S3

Absent amino acids  CEKVY

Common amino acids  R

Mass  619105

Pl  12.98

Basic residues  11

Acidic residues  1

Hydrophobic residues  9

Net charge  10

Boman Index  -17931

Hydrophobicity  -130.22

Aliphatic Index  39.11

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  125

Polar residues  14

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31540052

Title  Insight into the Antifungal Mechanism of Action of Human RNase N-terminus Derived Peptides

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  14153

DRACP is developed by Dr.Zheng's team.