Papiliocin [F5A]
General Information
DRACP ID DRACP03907
Peptide Name Papiliocin [F5A]
Sequence RWKIAKKIEKVGRNVRDGIIKAGPAVAVVGQAATVVK
Sequence Length 37
UniProt ID D8L127
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C177H309N55O45
Absent amino acids CFHLMSY
Common amino acids V
Mass 457008
Pl 11.82
Basic residues 9
Acidic residues 2
Hydrophobic residues 18
Net charge 7
Boman Index -4343
Hydrophobicity 6.76
Aliphatic Index 113.24
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 152.78
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26156126
Title Functional Roles of Aromatic Residues and Helices of Papiliocin in its Antimicrobial and Anti-inflammatory Activities
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14157