Papiliocin (1-22)[W2A,F5A]
General Information
DRACP ID DRACP03912
Peptide Name Papiliocin (1-22)[W2A,F5A]
Sequence RAKIAKKIEKVGRNVRDGIIKA
Sequence Length 22
UniProt ID D8L127
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C108H199N37O28
Absent amino acids CFHLMPQSTWY
Common amino acids K
Mass 283877
Pl 11.78
Basic residues 8
Acidic residues 2
Hydrophobic residues 9
Net charge 6
Boman Index -5961
Hydrophobicity -56.82
Aliphatic Index 110.91
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26156126
Title Functional Roles of Aromatic Residues and Helices of Papiliocin in its Antimicrobial and Anti-inflammatory Activities
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14174