Papiliocin (1-22)[W2F,F5W]
General Information
DRACP ID DRACP03913
Peptide Name Papiliocin (1-22)[W2F,F5W]
Sequence RFKIWKKIEKVGRNVRDGIIKA
Sequence Length 22
UniProt ID D8L127
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C122H208N38O28
Absent amino acids CHLMPQSTY
Common amino acids K
Mass 302999
Pl 11.78
Basic residues 8
Acidic residues 2
Hydrophobic residues 9
Net charge 6
Boman Index -5792
Hydrophobicity -64.55
Aliphatic Index 101.82
Half Life
Mammalian: 1 hour
Yeast: 2 min
E.coli: 2 min
Extinction Coefficient cystines 5500
Absorbance 280nm 261.9
Polar residues 3
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 26156126
Title Functional Roles of Aromatic Residues and Helices of Papiliocin in its Antimicrobial and Anti-inflammatory Activities
Doi Not available
Year 2015
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14175