This work is licensed under a Creative Commons Attribution 4.0 International License.
Dermaseptin-PT9 [D8K,E23K]
General Information
DRACP ID DRACP03927
Peptide Name Dermaseptin-PT9 [D8K,E23K]
Sequence GLWSKIKKAAKTAGKAALGFVNKMV
Sequence Length 25
UniProt ID A0A5P9NYS6
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C121H205N33O29S
Absent amino acids CDEHPQRY
Common amino acids K
Mass 304651
Pl 11.5
Basic residues 6
Acidic residues 0
Hydrophobic residues 12
Net charge 6
Boman Index -354
Hydrophobicity 14.8
Aliphatic Index 90
Half Life
Mammalian: 30 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 5500
Absorbance 280nm 229.17
Polar residues 6
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31635388
Title A Novel Dermaseptin Isolated from the Skin Secretion of Phyllomedusa tarsius and Its Cationicity-Enhanced Analogue Exhibiting Effective Antimicrobial and Anti-Proliferative Activities
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14234
This work is licensed under a Creative Commons Attribution 4.0 International License.