TW4A

General Information


DRACP ID  DRACP03933

Peptide Name   TW4A

Sequence  TRWRWWWRWRA

Sequence Length  11

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C86H112N28O13

Absent amino acids  CDEFGHIKLMNPQSVY

Common amino acids  W

Mass  192455

Pl  12.98

Basic residues  4

Acidic residues  0

Hydrophobic residues  6

Net charge  4

Boman Index  -4879

Hydrophobicity  -194.55

Aliphatic Index  9.09

Half Life 
  Mammalian: 1.9 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  27500

Absorbance 280nm  2750

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 31687796

Title  Therapeutic Potential of Trp-Rich Engineered Amphiphiles by Single Hydrophobic Amino Acid End-Tagging

Doi Not available

Year  2019

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  14242

DRACP is developed by Dr.Zheng's team.