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TW4A
General Information
DRACP ID DRACP03933
Peptide Name TW4A
Sequence TRWRWWWRWRA
Sequence Length 11
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C86H112N28O13
Absent amino acids CDEFGHIKLMNPQSVY
Common amino acids W
Mass 192455
Pl 12.98
Basic residues 4
Acidic residues 0
Hydrophobic residues 6
Net charge 4
Boman Index -4879
Hydrophobicity -194.55
Aliphatic Index 9.09
Half Life
Mammalian: 1.9 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 27500
Absorbance 280nm 2750
Polar residues 1
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 31687796
Title Therapeutic Potential of Trp-Rich Engineered Amphiphiles by Single Hydrophobic Amino Acid End-Tagging
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14242
This work is licensed under a Creative Commons Attribution 4.0 International License.