General Information


DRACP ID  DRACP03940

Peptide Name  

Sequence  RKWWK

Sequence Length  5

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C40H58N12O6

Absent amino acids  ACDEFGHILMNPQSTVY

Common amino acids  KW

Mass  87450

Pl  11.82

Basic residues  3

Acidic residues  0

Hydrophobic residues  2

Net charge  3

Boman Index  -2136

Hydrophobicity  -282

Aliphatic Index  0

Half Life 
  Mammalian: 30 hour
  Yeast: >20 hour
  E.coli: >10 hour

Extinction Coefficient cystines  11000

Absorbance 280nm  2750

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 24946217

Title  Tuning the antimicrobial pharmacophore to enable discovery of short lipopeptides with multiple modes of action

Doi Not available

Year  2014

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  14390

DRACP is developed by Dr.Zheng's team.