This work is licensed under a Creative Commons Attribution 4.0 International License.
NK-2 [R4P,T13P]
General Information
DRACP ID DRACP03942
Peptide Name NK-2 [R4P,T13P]
Sequence KILPGVCKKIMRPFLRRISKDILTGKK
Sequence Length 27
UniProt ID Q29075
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Amidation
Other Modification None
Chiral L
Physicochemical Information
Formula C143H256N42O32S2
Absent amino acids AEHNQWY
Common amino acids K
Mass 360393
Pl 11.82
Basic residues 9
Acidic residues 1
Hydrophobic residues 9
Net charge 8
Boman Index -4578
Hydrophobicity -18.89
Aliphatic Index 111.85
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 5
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29043494
Title Influence of Proline Substitution on the Bioactivity of Mammalian-Derived Antimicrobial Peptide NK-2
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 14420
This work is licensed under a Creative Commons Attribution 4.0 International License.