Cecropin A (1-8) + Fowlicidin-2 (6-20)

General Information


DRACP ID  DRACP03947

Peptide Name   Cecropin A (1-8) + Fowlicidin-2 (6-20)

Sequence  KWKLFKKIRFGRFLRKIRRFRPK

Sequence Length  23

UniProt ID  P01507 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Amidation

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C150H246N48O24

Absent amino acids  ACDEHMNQSTVY

Common amino acids  KR

Mass  349847

Pl  13.21

Basic residues  12

Acidic residues  0

Hydrophobic residues  9

Net charge  12

Boman Index  -8795

Hydrophobicity  -110.87

Aliphatic Index  67.83

Half Life 
  Mammalian: 1 hour
  Yeast: 2 min
  E.coli: 2 min

Extinction Coefficient cystines  5500

Absorbance 280nm  250

Polar residues  1

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32098142

Title  Hybridization With Insect Cecropin A (1-8) Improve the Stability and Selectivity of Naturally Occurring Peptides

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  14948

DRACP is developed by Dr.Zheng's team.