This work is licensed under a Creative Commons Attribution 4.0 International License.
Cyclo(Pro-Leu), S.sp. DKP-PL, Gancidin W
General Information
DRACP ID DRACP03961
Peptide Name Cyclo(Pro-Leu), S.sp. DKP-PL, Gancidin W
Sequence PL
Sequence Length 2
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Native peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C11H20N2O3
Absent amino acids ACDEFGHIKMNQRSTVWY
Common amino acids LP
Mass 24631
Pl 6.11
Basic residues 0
Acidic residues 0
Hydrophobic residues 1
Net charge 0
Boman Index 492
Hydrophobicity 110
Aliphatic Index 195
Half Life
Mammalian: 100 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 24047443
Title Antimycobacterial activity of cyclic dipeptides isolated from Bacillus sp N strain associated with entomopathogenic nematode
Doi Not available
Year 2014
Literature 2
Pubmed ID 35142498
Title Cyclo(l-proline-l-serine) Dipeptide Suppresses Seed Borne Fungal Pathogens of Rice: Altered Cellular Membrane Integrity of Fungal Hyphae and Seed Quality Benefits
Doi Not available
Year 2022
Literature 3
Pubmed ID 24122628
Title Antifungal activity of diketopiperazines and stilbenes against plant pathogenic fungi in vitro
Doi Not available
Year 2014
Literature 4
Pubmed ID 30270742
Title Chemical constituents from the deep sea-derived Streptomyces xiamenensis MCCC 1A01570 and their effects on RXR伪 transcriptional regulation
Doi Not available
Year 2020
Literature 5
Pubmed ID 22747978
Title Identification of antimicrobial compound, diketopiperazines, from a Bacillus sp N strain associated with a rhabditid entomopathogenic nematode against major plant pathogenic fungi
Doi Not available
Year 2012
Literature 6
Pubmed ID 28223778
Title Gancidin W, a potential low-toxicity antimalarial agent isolated from an endophytic Streptomyces SUK10
Doi Not available
Year 2017
Literature 7
Pubmed ID 312
Title
Year
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15017
This work is licensed under a Creative Commons Attribution 4.0 International License.