AGG-KR12-GAGG-KR12-G

General Information


DRACP ID  DRACP03962

Peptide Name   AGG-KR12-GAGG-KR12-G

Sequence  AGGKRIVQRIKDFLRGAGGKRIVQRIKDFLRG

Sequence Length  32

UniProt ID  P49913 

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer; Antibacterial; Antifungal



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C160H278N56O39

Absent amino acids  CEHMNPSTWY

Common amino acids  GR

Mass  416346

Pl  12.52

Basic residues  10

Acidic residues  2

Hydrophobic residues  12

Net charge  8

Boman Index  -8742

Hydrophobicity  -49.38

Aliphatic Index  97.5

Half Life 
  Mammalian: >20 hour
  Yeast: >20 hour
  E.coli: ?

Extinction Coefficient cystines  0

Absorbance 280nm  0

Polar residues  6

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 32153522

Title  Backbone Cyclization and Dimerization of LL-37-Derived Peptides Enhance Antimicrobial Activity and Proteolytic Stability

Doi Not available

Year  2020

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  15040

DRACP is developed by Dr.Zheng's team.