This work is licensed under a Creative Commons Attribution 4.0 International License.
LL-37 KR-12 [Q5A,D9A]
General Information
DRACP ID DRACP03964
Peptide Name LL-37 KR-12 [Q5A,D9A]
Sequence KRIVARIKAFLR
Sequence Length 12
UniProt ID P49913
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C68H123N23O13
Absent amino acids CDEGHMNPQSTWY
Common amino acids R
Mass 166726
Pl 12.81
Basic residues 5
Acidic residues 0
Hydrophobic residues 7
Net charge 5
Boman Index -3046
Hydrophobicity 17.5
Aliphatic Index 138.33
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29430821
Title Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15067
This work is licensed under a Creative Commons Attribution 4.0 International License.