This work is licensed under a Creative Commons Attribution 4.0 International License.
LL-37 KR-12 [Q5K,D9K]
General Information
DRACP ID DRACP03965
Peptide Name LL-37 KR-12 [Q5K,D9K]
Sequence KRIVKRIKKFLR
Sequence Length 12
UniProt ID P49913
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antibacterial; Antifungal
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C74H137N25O13
Absent amino acids ACDEGHMNPQSTWY
Common amino acids K
Mass 178144
Pl 12.83
Basic residues 7
Acidic residues 0
Hydrophobic residues 5
Net charge 7
Boman Index -4518
Hydrophobicity -77.5
Aliphatic Index 121.67
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 0
Absorbance 280nm 0
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29430821
Title Alanine and Lysine Scans of the LL-37-Derived Peptide Fragment KR-12 Reveal Key Residues for Antimicrobial Activity
Doi Not available
Year 2018
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15068
This work is licensed under a Creative Commons Attribution 4.0 International License.