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Z3
General Information
DRACP ID DRACP03978
Peptide Name Z3
Sequence KAAKKAWKAWKKAAKAWKKAA
Sequence Length 21
UniProt ID Not available
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C114H185N33O22
Absent amino acids CDEFGHILMNPQRSTVY
Common amino acids AK
Mass 272688
Pl 11.7
Basic residues 9
Acidic residues 0
Hydrophobic residues 12
Net charge 9
Boman Index -2667
Hydrophobicity -102.86
Aliphatic Index 42.86
Half Life
Mammalian: 1.3 hour
Yeast: 3 min
E.coli: 2 min
Extinction Coefficient cystines 16500
Absorbance 280nm 825
Polar residues 0
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 22057278
Title Relative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity
Doi Not available
Year 2012
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15135
This work is licensed under a Creative Commons Attribution 4.0 International License.