Z10

General Information


DRACP ID  DRACP03982

Peptide Name   Z10

Sequence  AAKKWAKAKKWAKAKKWAKAA

Sequence Length  21

UniProt ID  Not available

PubChem CID  Not available

Origin  Synthetic

Type  Synthetic peptide

Classification

  

Active ACP



Activity Information


Hemolytic Activity  Not available

Normal (non-cancerous) Cytotoxicity  Not available

Target  Not available

Affinity  Not available

Mechanism  Not available

Nature  Anticancer



Structure Information


PDB ID  Not available

Predicted Structure  Not available

Helicity  Not available

Linear/Cyclic  Linear

Disulfide/Other Bond  Not available

N-terminal Modification  Free

C-terminal Modification  Free

Other Modification  None

Chiral  L



Physicochemical Information


Formula  C114H185N33O22

Absent amino acids  CDEFGHILMNPQRSTVY

Common amino acids  AK

Mass  272688

Pl  11.7

Basic residues  9

Acidic residues  0

Hydrophobic residues  12

Net charge  9

Boman Index  -2667

Hydrophobicity  -102.86

Aliphatic Index  42.86

Half Life 
  Mammalian: 1.3 hour
  Yeast: 3 min
  E.coli: 2 min

Extinction Coefficient cystines  16500

Absorbance 280nm  825

Polar residues  0

Amino acid distribution



Literature Information


Literature 1

Pubmed ID 22057278

Title  Relative spatial positions of tryptophan and cationic residues in helical membrane-active peptides determine their cytotoxicity

Doi Not available

Year  2012

Patent

Patent ID Not available

Patent Title  Not available

Other Iinformation  Not available

Other Published ID  Not available




DBAASP ID  15142

DRACP is developed by Dr.Zheng's team.