This work is licensed under a Creative Commons Attribution 4.0 International License.
229E-HCoV-HR2P
General Information
DRACP ID DRACP03985
Peptide Name 229E-HCoV-HR2P
Sequence VVEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLKWL
Sequence Length 50
UniProt ID P15423
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C256H418N64O85
Absent amino acids CFGHMPR
Common amino acids L
Mass 662672
Pl 4.1
Basic residues 3
Acidic residues 6
Hydrophobic residues 19
Net charge -3
Boman Index -6837
Hydrophobicity -15.6
Aliphatic Index 126.6
Half Life
Mammalian: 4.4 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 8480
Absorbance 280nm 173.06
Polar residues 18
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 29415501
Title Peptide-Based Membrane Fusion Inhibitors Targeting HCoV-229E Spike Protein HR1 and HR2 Domains
Doi Not available
Year 2018
Literature 2
Pubmed ID 30989115
Title A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15166
This work is licensed under a Creative Commons Attribution 4.0 International License.