This work is licensed under a Creative Commons Attribution 4.0 International License.
HKU4-HR2P1 (1247-1282)
General Information
DRACP ID DRACP03988
Peptide Name HKU4-HR2P1 (1247-1282)
Sequence GPNFAEISKINTTLLDLSDEMAMLQEVVKQLNDSYI
Sequence Length 36
UniProt ID A3EX94
PubChem CID Not available
Origin Synthetic
Type Synthetic peptide
Classification
Active ACP
Activity Information
Hemolytic Activity Not available
Normal (non-cancerous) Cytotoxicity Not available
Target Not available
Affinity Not available
Mechanism Not available
Nature Anticancer; Antiviral
Structure Information
Helicity Not available
Linear/Cyclic Linear
Disulfide/Other Bond Not available
N-terminal Modification Free
C-terminal Modification Free
Other Modification None
Chiral L
Physicochemical Information
Formula C177H287N43O60S2
Absent amino acids CHRW
Common amino acids L
Mass 466609
Pl 3.82
Basic residues 2
Acidic residues 6
Hydrophobic residues 13
Net charge -4
Boman Index -4449
Hydrophobicity -6.39
Aliphatic Index 108.33
Half Life
Mammalian: 1.9 hour
Yeast: >20 hour
E.coli: >10 hour
Extinction Coefficient cystines 1490
Absorbance 280nm 42.57
Polar residues 10
Amino acid distribution
Literature Information
Literature 1
Pubmed ID 30646495
Title Potent MERS-CoV Fusion Inhibitory Peptides Identified From HR2 Domain in Spike Protein of Bat Coronavirus HKU4
Doi Not available
Year 2019
Patent
Patent ID Not available
Patent Title Not available
Other Iinformation Not available
Other Published ID Not available
External Code
DBAASP ID 15181
This work is licensed under a Creative Commons Attribution 4.0 International License.